Research

✨We lead the innovation of Magnetic Resonance Imaging and Focused Ultrasound Technology

Magnetic Resonance Imaging

Quantitative BBB Permeability and Microvascular Imaging (DCE Ktrans, IVIM)
(DCE Ktrans mapping, 3C IVIM PINN analysis in BBBO rats, NHP IVIM reconstruction)
Electrical Conductivity and Oxygen Metabolism Imaging (MREPT, OEF, qBOLD)
(MREPT experiments at KIRAMS, CCTV OEF reconstruction, qBOLD SO2 mapping review)
Imaging Biomarkers for Brain Disorders
(Parkinson’s disease MRI, cerebral microbleed detection, CBF and eGFR association, contrast MRI and PET in rodents)
AI Based Image Reconstruction and Synthesis
(Low field MRI reconstruction, sparse view CT reconstruction, synthetic PET)

Transcranial Acoustic Field Prediction and Skull Attenuation
(Skull attenuation review, HAS and k-Wave validation, skull phantom, real time acoustic simulation, Ultrasonics manuscript, PLOS ONE revision)
Beamforming and Treatment Planning
(ROT segmented beam patterns, NMM 3D ROI and multifocal beamforming, H-317 steering compensation, nonlinear pulse design, GBM thermal simulation)
Preclinical and Clinical Evaluation of BBB Opening
(NHP data analysis, BBBO segmentation and quantification, targeting error correction, BBBO clinical paper, clinical simulation paper)
Acoustic Coupling Assessment and Unshaved Coupling
(Coupling quantification, coupling through hair)

Image Guided Navigation and Robotic Systems
(Robotic arm integration with NMS, 3D depth camera image registration)
Acoustic Field Measurement and System Validation
(AIMS GUI validation, camera based acoustic pressure measurement, NMM system paper)
Novel Transducers and Bioelectrical Sensing Devices
(Acoustic lens, ultrasound needle, EIT reconstruction and denoising)

Personalized tACS Neuromodulation for iRBD
(Occipital alpha tACS, SimNIBS electric field modeling)
Ultrasound Neuromodulation and Glymphatic Modulation
(Glymphatic and OVST small animal studies)

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